R&D Systems代理AF6009 Human Cyr61/CCN1 Affinity Purified Polyclonal Ab (100 UG)-试剂-金山科研平台

R&D Systems代理AF6009 Human Cyr61/CCN1 Affinity Purified Polyclonal Ab (100 UG)

2025-06-26

货号：AF6009

品牌：R&D Systems

规格：100ug

目录价：￥5040.00

市场价格：￥4032.00

会员价格：￥4032.00

到货时间：3~4周

金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: Cyr61/CCN1 Long Name: Cysteine-Rich, Angiogenic Inducer 61 Aliases: CCN1; GIG1; IGFBP-10 Entrez Gene IDs: 3491 (Human); 16007 (Mouse); 83476 (Rat) Background: Cyr61

View Cyr61 IHC images. Cyr61, also known as IGFBP-10 and CCN1, is a 50 kDa matricellular glycoprotein that regulates the growth and adhesion of vascular endothelial cells, fibroblasts, and monocytes. Cyr61 induces VEGF upregulation, angiogenesis, and tumorigenesis through interactions with integrins alpha V beta 3, alpha V beta 5, alpha M beta 2, and alpha 6 beta 1. Cyr61 is cleaved by plasmin within its VWF domain which generates an N-terminal fragment that is not associated with the matrix but retains the ability to induce endothelial cell migration.

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