金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: S100A16 Long Name: S100 Calcium Binding Protein A16 Aliases: AAG13; DT1P1A7; S100F Entrez Gene IDs: 140576 (Human); 67860 (Mouse); 361991 (Rat) Background: S100A16

S100A16 (also S100F) is a 12 kDa member of the S100 family, EF-hand superfamily of Ca²⁺-binding proteins. By Northern blot, S100A16 is found in multiple tissue types; in brain, it is specifically found in astrocytes. Intracellularly, S100A16 is both nuclear and cytoplasmic and apparently exists as a homodimer, trimer, and tetramer. Human S100A16 is 103 amino acids (aa) in length. It contains two EF-hand motifs (aa 12 - 47 and 54 - 89) with only one high-affinity Ca²⁺-binding site (aa 67 - 78) and is believed to undergo phosphorylation at Ser103. Full-length human S100A16 shares 90% and 72% aa identity with canine and mouse S100A16, respectively.