金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: NCK1 Long Name: Non-catalytic Region of Tyrosine Kinase Adaptor Protein 1 Entrez Gene IDs: 4690 (Human); 179731 (Mouse); 300955 (Rat) Background: NCK1 NCK1 and NCK2 (non-catalytic region of tyrosine kinases) are widely expressed and promiscuous SH2/SH3-containing adaptor proteins. More than 60 interaction partners have been described for NCKs, including both cytoplasmic and nuclear proteins. NCKs have partially overlapping expression and function and share approximately 70% amino acid sequence identity. NCK1 is particularly involved in connecting receptor tyrosine kinase activation to actin cytoskeleton rearrangement, for example in B and T cell receptor signaling.