金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: Bad Long Name: Bcl-xL/Bcl-2 Associated Death Promoter Aliases: BBC6; BCL2L8 Entrez Gene IDs: 572 (Human); 12015 (Mouse); 64639 (Rat) Background: Bad The Bcl-2 family of proteins consists of both inhibitors and promoters of apoptosis. The relative ratios of pro- and anti-apoptotic Bcl-2 family proteins determine the sensitivity or resistance of cells to a variety of apoptotic signals. The pro-apoptoptic Bad (Bcl-2-antagonist of cell death) heterodimerizes strongly with Bcl-x, less strongly with Bcl-2, and not at all with Bax, Bcl-xS, Mcl-1, A1, or itself. When Bad dimerizes with Bcl-xL, Bax is displaced and its apoptosis-inducing ability is restored.