金山科研平台，产品价格货期咨询微信：jinshanbio Source:E. coli-derived, Ser82-Thr190 Accession #:Q6FHE7 N-terminal Sequence Analysis:Ser82 Structure:Disulfide-linked homodimer Purity:>97%, by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin Level:< 0.01 EU per 1 μg of the protein by the LAL method. Predicted Molecular Mass:12.4 kDa (monomer) Activity:Measured in a cell proliferation assay using NR6R‑3T3 mouse fibroblast cells. Raines, E.W. et al. (1985) Methods Enzymol. 109:749.The ED₅₀ for this effect is typically 1.5 - 6 ng/mL. Formulation:Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA.See Certificate of Analysis for details. Molecule Information: PDGF-BB Long Name: Platelet-derived Growth Factor BB Entrez Gene IDs: 5155 (Human); 24628 (Rat) Background: PDGF-A, -B, and -D The platelet-derived growth factor (PDGF) family of disulfide-linked dimeric proteins consists of four homodimeric proteins, PDGF-AA, PDGF-BB, PDGF-CC and PDGF-DD, and one heterodimeric protein, PDGF-AB. Members of this protein family act mainly on connective tissue. The dimeric isoforms of PDGF are expressed by different cell types and at different times during embryonic development. All PDGF isoforms are synthesized as inactive precursors and are processed to active forms that contain a PDGF/VEGF cysteine knot domain. Only PDGF-C and PDGF-D, also named spinal cord-derived growth factors SCDGF and SCDGF-B, also contain an N-terminal CUB domain. Mature PDGF dimers bind and induce the homo- or hetero-dimerization of two receptor tyrosine kinases (PDGF R alpha and R beta).