货号：14-675

品牌：Merck Millipore

规格：

目录价：￥4733.00

市场价格：￥4023.05

会员价格：￥3786.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: BrSK1, active View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 10 µg View All» Product Overview: N-terminal 6His-tagged, recombinant, human BrSK1 amino acids 2-end View All» Key Applications: Kinase Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» UniProt Summary: FUNCTION: SwissProt: Q8TDC3 # Required for the polarization of forebrain neurons which endows axons and dendrites with distinct properties, possibly by locally regulating phosphorylation of microtubule-associated proteins (By similarity). May be involved in the regulation of G2/M arrest in response to UV- or methyl methane sulfonate (MMS)- induced, but not IR-induced, DNA damage. Phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo.COFACTOR: Magnesium.SIZE: 794 amino acids; 86753 Da SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note=Nuclear in the absence of DNA damage. Translocated to the nucleus in response to UV- or MMS-induced DNA damage.TISSUE SPECIFICITY: Widely expressed, with highest levels in brain and testis. Protein levels remain constant throughout the cell cycle.SIMILARITY: SwissProt: Q8TDC3 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily. & Contains 1 protein kinase domain. & Contains 1 UBA domain. View All» Species: Human View All» Molecular Weight: 88.4kDa View All» Brand Family: Upstate View All» Source: expressed by baculovirus in Sf21 cells View All» Protein Target: BrSK1 View All» Storage Conditions: 6 months at -70°C from date of shipment View All» Target Sub-Family: CAMK View All» Gene Symbol:

• BRSK1

• SAD1

• KIAA1811

• FLJ43009
  View All» Product Name: BrSK1, active View All» Quality Assurance: routinely evaluated by phosphorylation of CHKtide (Catalog # 12-373) View All» UniProt Number: Q8TDC3 View All» Specific Activity: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. View All» Entrez Gene Number: NM_032430.1 View All» Purification Method: Ni²⁺/NTA-agarose View All»
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