货号:14-694
品牌:Merck Millipore
规格:
目录价:¥4368.00
市场价格:¥3712.80
会员价格:¥3494.40
金山科研平台,产品价格货期咨询微信:jinshanbio
Description:
NEK3, active
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Trade Name:
Upstate (Millipore)
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Qty/Pk:
10 µg
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Product Overview:
N-terminal 6His-tagged, recombinant, full length, human NEK3.
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Key Applications:
Kinase Assay
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Entrez Gene Summary:
In Aspergillus nidulans, lack of the serine/threonine kinase NimA (never in mitosis A) results in cell cycle arrest in G2, while overexpression causes the premature onset of mitotic events. The protein encoded by this gene is similar in sequence to the Aspergillus nidulans protein and may therefore play a role in mitotic regulation. However, the encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. Three transcript variants have been found for this gene, but the full-length nature of only two of them has been characterized.
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UniProt Summary:
FUNCTION: SwissProt: P51956 # Kinase that may play a role in mitotic regulation.COFACTOR: Magnesium.SIZE: 506 amino acids; 57705 Da SIMILARITY: SwissProt: P51956 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. NIMA subfamily. & Contains 1 protein kinase domain.
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Species:
Human
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Molecular Weight:
62.2kDa
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Brand Family:
Upstate
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Source:
Human NEK3, expressed by baculovirus in Sf21 cells.
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Protein Target:
NEK3
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Storage Conditions:
6 months at -70°C from date of shipment
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Target Sub-Family:
Misc
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Gene Symbol:
-
NEK3
-
HSPK36
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MGC29949
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Product Name:
NEK3, active
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Quality Assurance:
routinely evaluated by phosphorylation of MBP (13-104).
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UniProt Number:
P51956
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Specific Activity:
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
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Entrez Gene Number:
-
NM_002498.2
-
NM_152720.1
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Purification Method:
Ni2+/NTA-agarose
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