货号：14-700

品牌：Merck Millipore

规格：

目录价：￥3735.00

市场价格：￥3174.75

会员价格：￥2988.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: NEK11, active View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 10 µg View All» Product Overview: 6His-tagged, recombinant, human full length, NEK11 View All» Key Applications: Kinase Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Entrez Gene Summary: NEK11 belongs to the NIMA family of kinases, which are involved in DNA replication and genotoxic stress responses (Noguchi et al., 2002 [PubMed 12154088]).[supplied by OMIM] View All» UniProt Summary: FUNCTION: SwissProt: Q8NG66 # Possible role in S-phase checkpoint mechanism.COFACTOR: Manganese or magnesium.SIZE: 645 amino acids; 74162 Da SUBCELLULAR LOCATION: Nucleus. Nucleus, nucleolus. Note=Nuclear during interphase but moves to the polar microtubules during prometaphase and metaphase. Accumulates in the nucleolus in G1/S- arrested cells.TISSUE SPECIFICITY: Poorly expressed in cerebellum, trachea, lung, appendix, and uterus.DEVELOPMENTAL STAGE: Predominantly expressed at S/G2/M phase.PTM: Phosphorylated.SIMILARITY: SwissProt: Q8NG66 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. NIMA subfamily. & Contains 1 protein kinase domain. View All» Species: Human View All» Molecular Weight: 59.3kDa View All» Brand Family: Upstate View All» Source: expressed by baculovirus in Sf21 cells View All» Protein Target: NEK11 View All» Storage Conditions: 6 months at -70°C from date of shipment View All» Target Sub-Family: Misc View All» Gene Symbol:

• NEK11

• FLJ23495
  View All» Product Name: NEK11, active View All» Quality Assurance: routinely evaluated by phosphorylation of MBP (Catalog # 13-104) View All» UniProt Number: Q8NG66 View All» Specific Activity: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. View All» Entrez Gene Number:
  • NM_024800.3

  • NM_145910.2
    View All» Purification Method: Ni²⁺/NTA-agarose View All»
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