货号：14-736

品牌：Merck Millipore

规格：1ea

目录价：￥6618.00

市场价格：￥5625.30

会员价格：￥5294.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: TAO2, active View All» Trade Name: Chemicon (Millipore) View All» Qty/Pk: 10 µg View All» Product Overview: N-terminal 6His-tagged, recombinant, TAO2. TAO2 is a mitogen-activated protein kinase kinase kinase (MAP3K) that doubly phosphorylates and activates the MAP kinase kinases (MAP2Ks) MEK3 and MEK6. View All» Key Applications: Kinase Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» UniProt Summary: FUNCTION: SwissProt: Q9UL54 # Activates the JNK MAP kinase pathway through the specific activation of the upstream MKK3 and MKK6 kinases.COFACTOR: Magnesium (By similarity).SIZE: 1235 amino acids; 138251 Da SUBUNIT: Interacts with MKK3 and MKK6 (By similarity). Self- associates.SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane; Multi-pass membrane protein (Potential). Note=Found to be perinuclear and localized to vesicular compartment.TISSUE SPECIFICITY: Ubiquitously expressed, with a higher level of expression in testis and brain.SIMILARITY: SwissProt: Q9UL54 ## Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. & Contains 1 protein kinase domain. View All» Species: Human View All» Molecular Weight: 138.3 kDa View All» Brand Family: Chemicon View All» Source: expressed in Sf21 cells View All» Protein Target: TAO2 View All» Presentation: 10 μg of enzyme in 100 μL of 50 mM Tris/HCl pH7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij 35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. View All» Storage Conditions: Stable for 6 months at -70°C from date of shipment. For maximum recovery of product, centrifuge original vial prior to removing the cap. Rapidly thaw the vial under cold water and immediately place on ice. Aliquot unused material into pre-chilled microcentrifuge tubes and immediately snap-freeze the vials in liquid nitrogen prior to re-storage at -70°C. View All» Target Sub-Family: STE View All» Promotional Text: This enzyme is part of KinaseProfiler™, a custom inhibitor selectivity discovery service. View All» Gene Symbol:

• TAOK2

• TAO1

• TAO2

• PSK

• PSK1

• MAP3K17

• KIAA0881

• hKFC-C

• PSK-1
  View All» Product Name: TAO2, active View All» Quality Assurance: Routinely evaluated by phosphorylation of 0.8 mg/ml myelin basic protein (MBP). Purity was assessed by SDS-PAGE and Coomassie blue staining using 3 μg of TAO2. View All» UniProt Number: Q9UL54 View All» Specific Activity: 1562 U/mg, where one unit of TOA2 activity is defined as 1 nmol phosphate incorporated into 0.8 mg/mL myelin basic per minute at 30°C with a final ATP concentration of 100 μM. View All» Entrez Gene Number:
  • NM_004783.2

  • NM_016151.2
    View All» Purity: Purity 84% by SDS PAGE and Coomassie blue staining. View All» Purification Method: Ni²⁺/NTA-agarose View All»
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