Merck Millipore代理14-739M TLK2 Protein, active, 10 µg;store at -80℃

2025-06-28

货号:14-739M

品牌:Merck Millipore

规格:250Ug

目录价:¥42566.00

市场价格:¥36181.10

会员价格:¥34052.80

金山科研平台,产品价格货期咨询微信:jinshanbio Description: TLK2, active View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 250 µg View All» Product Overview: N-terminal 6His-tagged, recombinant, 388-end, human TLK2. View All» Key Applications: Kinase Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Entrez Gene Summary: The Tousled-like kinases, first described in Arabidopsis, are nuclear serine/threonine kinases that are potentially involved in the regulation of chromatin assembly.[supplied by OMIM] View All» UniProt Summary: FUNCTION: SwissProt: Q86UE8 # Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S- phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly.COFACTOR: Magnesium.SIZE: 772 amino acids; 87661 Da SUBUNIT: Heterodimerizes with TLK1. Interacts with ASF1A and ASF1B.SUBCELLULAR LOCATION: Nucleus.TISSUE SPECIFICITY: Widely expressed. Present in fetal placenta, liver, kidney, pancreas, heart and skeletal muscle. Also found in adult cell lines.SIMILARITY: SwissProt: Q86UE8 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain. View All» Species: Human View All» Molecular Weight: 48.8 kDa View All» Brand Family: Upstate View All» Source: Expressed by baculovirus in Sf21 cells. View All» Protein Target: TLK2 View All» Storage Conditions: Stable for 6 months at -70°C from date of shipment. For maximum recovery of product, centrifuge original vial prior to removing the cap. Rapidly thaw the vial under cold water and immediately place on ice. Aliquot unused material into pre-chilled microcentrifuge tubes and immediately snap-freeze the vials in liquid nitrogen prior to re-storage at -70°C. View All» Target Sub-Family: Misc View All» Promotional Text: This enzyme is part of KinaseProfiler™, a custom inhibitor selectivity discovery service. View All» Gene Symbol:

  • TLK2

  • MGC44450

  • PKU-alpha

  • PKU-ALPHA

    View All» Product Name: TLK2, active View All» Alternate Names: tousled-like kinase 2 View All» UniProt Number: Q86UE8 View All» Specific Activity: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. View All» Packaging: Also available in 10 μg size (cat#14-739) and in bulk (cat# 14-739-K). View All» Entrez Gene Number: NM_006852.2 View All» Purification Method: Ni2+/NTA-agarose View All»

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