货号：14-745M

品牌：Merck Millipore

规格：250Ug

目录价：￥42566.00

市场价格：￥36181.10

会员价格：￥34052.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: TAO3, active View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 250 µg View All» Product Overview: N-terminal 6His-tagged, recombinant, human TAO3 amino acids 1-411; N47S. View All» Key Applications: Kinase Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» UniProt Summary: FUNCTION: SwissProt: Q9H2K8 # Inhibits the basal activity of Jun kinase. Negatively regulated by epidermal growth factor (EGF). When overexpressed, may activate ERK1/ERK2 and JNK/SAPK.SIZE: 898 amino acids; 105406 Da SUBUNIT: Self-associates.SUBCELLULAR LOCATION: Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Also localized to the peripheral cell membrane.TISSUE SPECIFICITY: Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver.PTM: Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.SIMILARITY: SwissProt: Q9H2K8 ## Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. & Contains 1 protein kinase domain. View All» Species: Human View All» Molecular Weight: 50.2 kDa View All» Brand Family: Upstate View All» Source: Recombinant, human TAO3 amino acids 1-411; N47S. Expressed by baculovirus in Sf21 cells. View All» Protein Target: TAO3 View All» Presentation: 10 μg of enzyme in 6.3 μL of 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij 35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. View All» Storage Conditions: Stable for 6 months at -70°C from date of shipment. For maximum recovery of product, centrifuge original vial prior to removing the cap. Rapidly thaw the vial under cold water and immediately place on ice. Aliquot unused material into pre-chilled microcentrifuge tubes and immediately snap-freeze the vials in liquid nitrogen prior to re-storage at -70°C. View All» Target Sub-Family: STE View All» Promotional Text: This enzyme is part of KinaseProfiler™, a custom inhibitor selectivity discovery service. View All» Gene Symbol:

• TAOK3

• JIK

• hKFC-A

• MAP3K18

• DPK

• KDS

• DKFZp666H245

• FLJ31808
  View All» Product Name: TAO3, active View All» Quality Assurance: Routinely evaluated by phosphorylation of 0.8 mg/mL myelin basic protein. Purity was assessed by SDS-PAGE and Coomassie blue staining using 3μg of TAO3. View All» UniProt Number: Q9H2K8 View All» Specific Activity: 915U/mg, where one unit of TAO3 activity is defined as 1nmol phosphate incorporated into 0.8mg/ml myelin basic protein per minute at 30°C with a final ATP concentration of 100μM. View All» Packaging: Also available in 10 μg size (cat#14-745) and in bulk (cat# 14-745-K). View All» Entrez Gene Number: NM_016281.3 View All» Purity: Purity 84% by SDS-PAGE and Coomassie blue staining. View All» Purification Method: Ni²⁺/NTA-agarose View All»
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