货号：14-752M

品牌：Merck Millipore

规格：1ea

目录价：￥42566.00

市场价格：￥36181.10

会员价格：￥34052.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: GRK7, active View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 250 µg View All» Product Overview: N-terminal 6His-tagged, recombinant, full length human GRK7 expressed by baculovirus in Sf21 cells. View All» Key Applications: Kinase Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Entrez Gene Summary: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. It is specifically expressed in the retina and the encoded protein has been shown to phosphorylate cone opsins and initiate their deactivation. View All» UniProt Summary: FUNCTION: SwissProt: Q8WTQ7 # Phosphorylates cone opsins thereby initiating their deactivation.SIZE: 553 amino acids; 62212 Da SUBCELLULAR LOCATION: Membrane; Lipid-anchor.TISSUE SPECIFICITY: Retina. Cones and rod.SIMILARITY: SwissProt: Q8WTQ7 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 protein kinase domain. & Contains 1 RGS domain. View All» Species: Human View All» Molecular Weight: 66 kDa View All» Brand Family: Upstate View All» Source: Recombinant, full length human GRK7 expressed by baculovirus in Sf21 cells. View All» Protein Target: GRK7 View All» Presentation: 10μg of recombinant protein in 100 μl of 50 mM Tris-HCl pH 8.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. View All» Storage Conditions: Stable for 6 months at -70°C from date of shipment. For maximum recovery of product, centrifuge original vial prior to removing the cap. View All» Target Sub-Family: AGC View All» Promotional Text: This enzyme is part of KinaseProfiler™, a custom inhibitor selectivity discovery service. View All» Gene Symbol:

• GRK7

• GPRK7
  View All» Product Name: GRK7, active View All» Quality Assurance: Routinely evaluated by phosphorylation of 2 mg/mL casein. Purity was assessed by SDS-PAGE and Coomassie blue staining using 3μg of GRK7. View All» UniProt Number: Q8WTQ7 View All» Specific Activity: 381U/mg, where one unit of GRK7 activity is defined as 1nmol phosphate incorporated into 2mg/ml casein per minute at 30°C with a final ATP concentration of 100μM. View All» Packaging: Also available in 10 μg size (cat#14-752) and in bulk (cat# 14-752-K). View All» Entrez Gene Number: NM_139209.2 View All» Purification Method: Purified using Ni²⁺/NTA agarose. Purity 99% by SDS-PAGE and Coomassie blue staining. View All»
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