金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: Insulin R/CD220 Long Name: Insulin Receptor Aliases: CD220; INSR Entrez Gene IDs: 3643 (Human); 16337 (Mouse) Background: Insulin Receptor The insulin receptor is a type I transmembrane receptor tyrosine kinase. Ligand binding results in receptor autophosphorylation, and subsequent downstream signaling important in metabolic regulation, cell growth, differentiation, and apoptosis. Mutations in the insulin receptor gene have been linked to insulin-resistant diabetes mellitus and noninsulin-dependent diabetes mellitus.