货号:14-758M
品牌:Merck Millipore
规格:
目录价:¥35565.00
市场价格:¥30230.25
会员价格:¥28452.00
金山科研平台,产品价格货期咨询微信:jinshanbio
Description:
Ret (V804L), active
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Trade Name:
Upstate (Millipore)
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Qty/Pk:
250 µg
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Product Overview:
N-Terminal GST-tagged, recombinant, human Ret amino acids 658 – end containing the V804L mutation.
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Background Information:
The V804L mutation has been identified in patients with familial medullary thyroid carcinoma (FMTC) (Lombardo F. et al., (2002), JCEM, 87, 1674-1680; Lesueur F. et al, (2005), JCEM, 90, 3454-3457).
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Key Applications:
Kinase Assay
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Species:
Human
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Molecular Weight:
79.2 kDa
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Brand Family:
Upstate
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Source:
Expressed by baculovirus in Sf21 insect cells.
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Protein Target:
Ret
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Presentation:
50mM Tris-HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
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Storage Conditions:
Store -70°C. For maximum recovery of product, centrifuge original vial prior to removing the cap. Rapidly thaw the vial under cold water and immediately place on ice. Aliquot unused material into pre-chilled microcentrifuge tubes and immediately snap-freeze the vials in liquid nitrogen prior to re-storage at -70°C.
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Target Sub-Family:
TK
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Promotional Text:
This enzyme is part of KinaseProfiler™, a custom inhibitor selectivity discovery service.
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Gene Symbol:
-
RET
-
CRET
-
CDHF12
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Product Name:
Ret (V804L), active
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Quality Assurance:
Routinely evaluated by phosphorylation of CHKtide.
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UniProt Number:
-
P07949
-
P35546 (mouse)
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Specific Activity:
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
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Packaging:
Also available in 10 μg size (cat#14-758) and in bulk (cat# 14-758-K).
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Entrez Gene Number:
NM_000323
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Purification Method:
Glutathione agarose affinity chromatography
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