金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: DCIR/CLEC4A Long Name: Dendritic Cell Immunoreceptor Aliases: CLEC4A; CLECSF6; DDB27; LLIR Entrez Gene IDs: 50856 (Human); 26888 (Mouse) Background: DCIR/CLEC4A DCIR, also known as lectin-like immunoreceptor (LLIR), is a type II transmembrane protein belonging to the C-type lectin domain family and is designated CLEC4A (previously designated CLECSF6). Four transcript variants encoding distinct isoforms have been identified. DCIR contains one carbohydrate recognition domain in its C-terminal extracellular domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain. DCIR is expressed on dendritic cells, B cells, monocytes/macrophages and granulocytes.