货号：14-812

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: UbcH6 Conjugating Enzyme View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 100 µg View All» Product Overview: The His6-fusion protein of UbcH6 charges and supports ubiquitinylation in vitro. UbcH6 is an integral membrane protein localized to the endoplasmic reticulum (ER), and possibly the nuclear envelope. UbcH6 may be involved in the degradation of unprocessed protein precursors that are not translocated through the rough ER, turnover of membrane proteins such as cytochrome P450 2E14, and the control of transcription factors. Typical enzyme concentration to support conjugation in vitro is 100nM to 1μM depending upon conditions. View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Entrez Gene Summary: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. View All» UniProt Summary: FUNCTION: SwissProt: P51965 # Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins.SIZE: 193 amino acids; 21404 Da SUBUNIT: Interacts with RNF14.SIMILARITY: SwissProt: P51965 ## Belongs to the ubiquitin-conjugating enzyme family. View All» Species: Human View All» Molecular Weight: 21 kDa View All» Brand Family: Upstate View All» Source: Recombinant human UbcH6 Conjugating Enzyme expressed in E. coli. View All» Storage Conditions: Stable for 1 year at -80°C from date of shipment. Avoid multiple freeze/thaw cycles. After initial defrost, aliquot into individual tubes and refreeze at -80°C. View All» Gene Symbol:

• UBE2E1

• UbcH6

• UBCH6
  View All» Product Name: UbcH6 Conjugating Enzyme View All» UniProt Number: P51965 View All» Entrez Gene Number:
  • NM_003341.3

  • NM_182666.1
    View All» Purity: >95% by SDS-PAGE View All»
    © 金山科研平台是专业的授权总代理区域代理经销平台。
    © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
    © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
    © 本文地址：https://www.16ao.com/thread-146699.htm
    © Merck Millipore代理14-812 Ubiquitin conjugating enzyme UbcH6, 6His;已停产，产品报价联系微信jinshanbio