货号：14-870

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: UbcH3, recombinant View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 100 µg View All» Product Overview: Recombinant fusion protein containing human UbcH3 with an N-terminal His-tag, expressed in E. coli. View All» Key Applications: Activity Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Entrez Gene Summary: The protein encoded by this gene is a member of the ubiquitin-conjugating enzyme family. Ubiquitin-conjugating enzyme catalyzes the covalent attachment of ubiquitin to other proteins. This protein is a part of the large multiprotein complex, which is required for ubiquitin-mediated degradation of cell cycle G1 regulators, and for the initiation of DNA replication. View All» UniProt Summary: FUNCTION: SwissProt: P49427 # Catalyzes the covalent attachment of ubiquitin to other proteins. May be involved in degradation of katenin.SIZE: 236 amino acids; 26737 Da SUBUNIT: Interacts with SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex. When phosphorylated, interacts with beta-TrCP (BTRC).SIMILARITY: SwissProt: P49427 ## Belongs to the ubiquitin-conjugating enzyme family. View All» Species: Human View All» Molecular Weight: 30 kDa View All» Brand Family: Upstate View All» Source: Expressed in E. coli View All» Presentation: 100 µg recombinant UbcH3 in 100 µL of 50mM Tris-HCl, pH 7.5, 270mM Sucrose, 150mM NaCl, 0.1mM EGTA, 0.1% 2-mercaptoethanol, 0.02% Brij-35, 0.2mM PMSF, and 1mM Benzamidine. Frozen solution. View All» Storage Conditions: Stable for 2 years at -70°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. View All» Gene Symbol:

• CDC34

• UBE2R1

• E2-CDC34

• UBC3
  View All» Product Name: UbcH3, recombinant View All» Concentration: 1 mg/mL View All» Quality Assurance: Routinely evaluated by ubiquitin assay View All» UniProt Number: P49427 View All» Entrez Gene Number: NM_004359.1 View All» Purity: ~90% by SDS PAGE and Coomassie blue staining. View All» Purification Method: ProBond Resin chromatography View All»
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