货号：14-901M

品牌：Merck Millipore

规格：250Ug

目录价：￥42566.00

市场价格：￥36181.10

会员价格：￥34052.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: PIP4K2α, active View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 250 µg View All» Product Overview: N-terminal 6His-tagged, recombinant human PIP4K2α, full length. View All» Key Applications: Kinase Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Entrez Gene Summary: Phosphatidylinositol-5,4-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. The protein encoded by this gene is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. View All» UniProt Summary: FUNCTION: Catalyzes the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol-4,5-biphosphate.CATALYTIC ACTIVITY: ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.SUBUNIT STRUCTURE: HomodimerTISSUE SPECIFICITY: Expressed ubiquitously, with high levels in the brain. Present in most tissues, except notably skeletal muscle and small intestine. SIMILARITY: Contains 1 PIPK domain. View All» Species: Human View All» Molecular Weight: 51kDa View All» Brand Family: Upstate View All» Source: Expressed by baculovirus in Sf21 insect cells View All» Protein Target: PIP4K2α View All» Presentation: 10µg of enzyme in 50mM Tris/HCl pH8.0, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 0.2mM PMSF, 1mM benzamidine, 0.1% 2-mercaptoethanol. Frozen solution. View All» Storage Conditions: 6 months at -70°C View All» Target Sub-Family: PIPK View All» Promotional Text: This enzyme is part of KinaseProfiler™, a custom inhibitor selectivity discovery service. View All» Gene Symbol:

• PIP4K2A

• PIP5K2

• PIP5K2A
  View All» Product Name: PIP4K2α, active View All» Quality Assurance: Routinely evaluated in the PIProfiler. View All» UniProt Number: P48426 View All» Specific Activity: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. View All» Packaging: Also available in 10 μg size (cat#14-901) and in bulk (cat# 14-901-K). View All» Entrez Gene Number: NM_005028 View All» Purification Method: Ni²⁺/NTA-agarose View All»
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  © Merck Millipore代理14-901M PIP4K2α Protein, active, 10 µg;store at -80℃，产品报价联系微信jinshanbio