货号：14-911M

品牌：Merck Millipore

规格：1ea

目录价：￥42566.00

市场价格：￥36181.10

会员价格：￥34052.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Aurora C, active View All» Qty/Pk: 250 µg View All» Product Overview: Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Plays also a role in meiosis and more particularly in spermatogenesis. Has redundant cellular functions with AURKB and can rescue an AURKB knockdown. Like AURKB, AURKC phosphorylates histone H3 at 'Ser-10' and 'Ser-28'. Phosphorylates TACC1, another protein involved in cell division, at 'Ser-228'. View All» Key Applications: Kinase Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Species: Human View All» Molecular Weight: 36 kDa View All» Quality Assurance: Routinely evaluated by phosphorylation of the peptide AKRRRLSSLRA View All» Brand Family: Upstate View All» Source: N-terminal 6His-tagged, recombinant, human Aurora C amino acids 35-end and N-terminal GST-tagged, recombinant, human INCENP, amino acids 821–end. Co-expressed by baculovirus in Sf21 insect cells View All» Presentation: Protein in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. View All» UniProt Number: Q9UQB9 View All» Specific Activity: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. View All» Storage Conditions: 6 months at -70°C View All» Promotional Text: This enzyme is part of KinaseProfiler™, a custom inhibitor selectivity discovery service. View All» Packaging: Also available in 10μg size as catalog # 14-911 and in 250 μg as catalog # 14-911-K. View All» Gene Symbol:

• AURKC

• AurC

• STK13

• Aur3
  View All» Product Name: Aurora C, active View All» Entrez Gene Number: NM_020238.2 View All» Purification Method: Purified using Ni2+/NTA agarose View All»
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  © Merck Millipore代理14-911M Aurora C Protein, active, 10 µg;store at -80℃，产品报价联系微信jinshanbio