货号：14-923M

品牌：Merck Millipore

规格：

目录价：￥35739.00

市场价格：￥30378.15

会员价格：￥28591.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Flt1, active View All» Qty/Pk: 250 µg View All» Product Overview: This protein encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia. View All» Key Applications: Kinase Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Species: Human View All» Molecular Weight: 89 kDa View All» Brand Family: Upstate View All» Source: N-terminal GST-tagged, recombinant, human Flt1 amino acids 783-end, expressed by baculovirus in Sf21 insect cells. View All» Protein Target: Flt1 View All» Presentation: 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. View All» Storage Conditions: 6 months at -70°C View All» Target Sub-Family: TK View All» Promotional Text: This enzyme is part of KinaseProfiler™, a custom inhibitor selectivity discovery service. View All» Gene Symbol:

• FLT

• FLT-1

• VEGFR1

• VEGFR-1
  View All» Product Name: Flt1, active View All» Quality Assurance: Routinely evaluated by phosphorylation of peptide KKKSPGEYVNIEFG View All» UniProt Number: P17948 View All» Specific Activity: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. View All» Packaging: Also available in 10μg size as catalog # 14-923 and in bulk as catalog # 14-923-K. View All» Entrez Gene Number: AF063657 View All» Purification Method: Purified using glutathione sepharose. View All»
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