货号：16-242

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-CD3ε, clone APA1/1, Alexa Fluor® 555 conjugate View All» Replaces: CBL1317P View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: Recognizes CD3ε. Clone APA1/1 has been demonstrated to recognize a site on CD3ε that is exposed upon engagement of the T-cell Receptor complex. View All» Molecular Weight: 23kDa View All» Immunogen: Purified human CD3ε View All» Isotype: IgG2bκ View All» Species Reactivity:

• Human

• Mouse
  View All» Quality Assurance: Routinely evaluated by immunoblot. View All» Purification Method: Protein G purfied View All» Storage Conditions: 1 year at 4°C from date of shipment View All» UniProt Number: P07766 View All» Entrez Gene Number: NM_000733.2 View All» Gene Symbol:
  • CD3E

  • T3E

  • TCRE
    View All» Usage Statement:
    • Alexa Fluor® is a registered trademark of Molecular Probes, Inc.

    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      View All» Key Applications:
      • Flow Cytometry

      • Western Blotting
        View All» Entrez Gene Summary: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. View All» UniProt Summary: FUNCTION: SwissProt: P07766 # The CD3 complex mediates signal transduction.SIZE: 207 amino acids; 23147 Da SUBUNIT: The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta.SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.SIMILARITY: SwissProt: P07766 ## Contains 1 Ig-like (immunoglobulin-like) domain. & Contains 1 ITAM domain. View All» Brand Family: Upstate View All» Product Name: Anti-CD3ε, clone APA1/1, Alexa Fluor® 555 conjugate View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Mouse View All»
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