货号：16-318

品牌：Merck Millipore

规格：200UL

目录价：￥6588.00

市场价格：￥5599.80

会员价格：￥5270.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Akt/PKB Antibody, PH Domain, clone SKB1, Magnetic Bead Conjugate | 16-318 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: Recognizes Akt1/PKBα. View All» Molecular Weight: ~ 60 kDa observed View All» Immunogen: GST-fusion protein corresponding to residues 1-149 of human Akt1 View All» Isotype: IgG View All» Background Information: Akt (protein kinase B), a serine/threonine kinase, has emerged as a critical enzyme in signal transduction pathways involved in cell proliferation, apoptosis, angiogenesis, and diabetes. In mammals three isoforms of Akt (α, β, γ or Akt 1, 2, 3) are reported that exhibit a high degree of homology, but differ slightly in the localization of their regulatory phosphorylation sites. Akt α is the predominant isoform in most tissues, whereas the highest expression of Akt β is observed in the insulin-responsive tissues, and Akt γ is abundant in brain tissue. Each Akt isoform is composed of three functionally distinct regions: an N-terminal pleckstrin homology (PH) domain that provides a lipid-binding module to direct Akt to PIP2 and PIP3, a central catalytic domain, and a C-terminal hydrophobic motif. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Species Reactivity Note: Human, Mouse, Rat View All» Control: NIH3T3 whole cell lysate stimulated with 50 ng/mL PDGF (5 minutes) View All» Quality Assurance: Evaluated by immunoprecipitation on 250 μg of NIH3T3 whole cell lysate stimulated with 50 ng/mL PDGF (5 minutes). View All» Purification Method: Protein G Chromatography View All» Presentation: 20% slurry; 1X PBS, 0.05% sodium azide.Sufficient for 10 IPs. View All» Storage Conditions: Stable for 1 year at 2-8ºC from date of receipt. View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Immunoprecipitation View All» Product Name: Anti-Akt/PKB, PH Domain, clone SKB1, Magnetic Bead Conjugate View All» Antibody Type: Monoclonal Antibody View All» Qty/Pk: 200 μL View All» Format: Purified View All» Host: Mouse View All»
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  © Merck Millipore代理16-318 Anti-Akt/PKB Antibody, PH Domain, clone SKB1, Magnetic Bead Conjugate;store at +2℃ to +8℃，产品报价联系微信jinshanbio