货号：17-330

品牌：Merck Millipore

规格：

目录价：￥3662.00

市场价格：￥3112.70

会员价格：￥2929.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Histone Methyltransferase Assay Reagent Kit View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 1 kit View All» Product Overview: Accessory reagent kit for the analysis of histone methyltransferase activity. View All» Key Applications: Histone Methyltransferase Assay (HMT) View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Entrez Gene Summary: In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. View All» UniProt Summary: FUNCTION: SwissProt: P50135 # Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine.SIZE: 292 amino acids; 33295 Da SUBUNIT: Monomer.SUBCELLULAR LOCATION: Cytoplasm.SIMILARITY: SwissProt: P50135 ## Belongs to the methyltransferase superfamily. HNMT family. View All» Brand Family: Upstate View All» Gene Symbol:

• HNMT

• HMT

• HNMT-S2

• HNMT-S1
  View All» Product Name: Histone Methyltransferase Assay Reagent Kit View All» Quality Assurance: Routinely evaluated by methylating core histones with PRMT1, active (14-474). View All» Components:
  • 5X HMTase Assay Buffer

  • Core histones

  • P81 Phosphocellulose Squares (Cat.# 20-134)
    View All» UniProt Number: P50135 View All» Packaging: Kit capacity: 100 assays View All» Entrez Gene Number:
    • NM_001024074.1

    • NM_001024075.1

    • NM_006895.2
      View All»
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