金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: PBEF/Visfatin Long Name: Pre-B-Cell Colony-Enhancing Factor 1 Aliases: NAmPRTase; NAMPT; PBEF1; Visfatin Entrez Gene IDs: 10135 (Human); 59027 (Mouse); 297508 (Rat) Background: PBEF PBEF, also called Nampt or visfatin, is a ubiquitous 52 kDa nicotinamide phosphoribosyltransferase. PBEF is the rate-limiting component in the biosynthesis of NAD+, and functions in the cytoplasm to regulate energy metabolism during stress responses and immune activation. Although it lacks a signal sequence, PBEF appears to be secreted by visceral adipose and functions as a noncompetitive insulin mimetic. Mouse PBEF shows 96% and > 99% aa identity with human and rat PBEF, respectively.