金山科研平台，产品价格货期咨询微信：jinshanbio Molecule Information: ADAM19 Long Name: A Disintegrin and Metalloprotease-like Domain 19 Aliases: Meltrin beta Entrez Gene IDs: 8728 (Human); 11492 (Mouse) Background: ADAMs (A Disintegrin and Metalloprotease) Members of the ADAM or MDC (Metalloprotease, Disintegrin, Cysteine-rich) family contain pro, metalloprotease-like, disintegrin-like, cysteine-rich, transmembrane and cytoplasmic domains. They play a fundamental role in diverse processes such as asthma, development, angiogenesis and cancer through their activities in cell adhesion/fusion, membrane protein shedding, and signal transduction. Over 30 members have been identified and about half of them are active metalloproteases such as ADAM8, 9, 10, 12 and 17/TACE.