货号:23-033
品牌:Merck Millipore
规格:10Ug
目录价:¥7696.00
市场价格:¥6541.60
会员价格:¥6156.80
金山科研平台,产品价格货期咨询微信:jinshanbio
Description:
MDM2 (c-Myc tagged), active
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Trade Name:
Upstate (Millipore)
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Qty/Pk:
10 µg
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Background Information:
MDM2 is an E3 ubiquitin ligase that regulates the turnover of several cellular factors including the p53 tumour suppressor protein and notably MDM2 itself. The suppression of p53 activity by an amplified Mdm2 gene has been observed in many tumours, including soft tissue sarcomas, osteosarcomas and breast tumours.
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Key Applications:
Enzyme Assay
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Species:
Human
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Cascade Component:
E3
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Brand Family:
Upstate
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Specific Activity:
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
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Long Description:
N-terminal c-Myc, GST-tagged, recombinant human MDM2 full length, expressed in E.coli. Purified using glutathione sepharose followed by gel filtration.
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Product Name:
MDM2 (c-Myc tagged), active
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Entrez Gene Number:
AF527840 (GenBank Number)
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Alternate Names:
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Double minute 2 protein
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p53-binding protein Mdm2
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Hdm2
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Purification Method:
Purified using glutathione sepharose followed by gel filtration.
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