货号：23-042-K

品牌：Merck Millipore

规格：

目录价：￥410.00

市场价格：￥348.50

会员价格：￥328.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Src View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: BULK View All» Background Information: Src is a ubiquitously expressed, non-receptor tyrosine kinase that plays a pivotal role in numerous cellular processes such as proliferation, migration, and transformation. Due to its critical function in regulating signal transduction pathways, Src activity is tightly controlled through reversible phosphorylation and dephosphorylation events and down-regulation by ubiquitin-dependent degradation. Dysfunction of Src, through overexpression or increased activation has profound effects on basic cellular functions. Elevated Src expression and/or activation is evident across a wide range of solid tumour types and has been strongly implicated in the development, maintenance, progression, and metastatic spread of several human cancers, such as prostate, lung, breast, and colorectal cancer. View All» Key Applications: Enzyme Assay View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Species: Human View All» Cascade Component: Substrate View All» Brand Family: Upstate View All» Product Name: Src View All» Alternate Names:

• Proto-oncogene c-Src

• pp60c-src

• SRC1
  View All» Specific Activity: For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. View All» Long Description: N-terminal c-Myc, 6His- tagged, recombinant human Src full length, expressed by baculovirus in Sf21 insect cells. Purified using immobilized metal affinity chromatography. View All» Entrez Gene Number: NM_198291 (GenBank Number) View All» Purification Method: Purified using immobilized metal affinity chromatography. View All»
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