Merck Millipore代理33-039 PI3-K (CII) HTRF Assay - 5-plate kit

2025-06-28

货号:33-039

品牌:Merck Millipore

规格:

目录价:¥93856.00

市场价格:¥79777.60

会员价格:¥75084.80

金山科研平台,产品价格货期咨询微信:jinshanbio Description: PI 3-Kinase Class II HTRF Assay View All» Trade Name: Upstate (Millipore) View All» Qty/Pk: 1920 wells View All» Key Applications: Kinase Assay View All» Species Reactivity:

  • Human

  • Mouse

    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Entrez Gene Summary: Phosphoinositide 3-kinase-C2 proteins generate phosphatidylinositol 3-phosphate (PtdIns3P) and phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) that act as second messengers. This protein belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is sensitive to low nanomolar levels of the inhibitor wortmanin. The C2 domain of this protein was shown to bind phospholipids but not Ca2+, which suggests that this enzyme may function in a calcium-independent manner. View All» Components:
    • Reaction Buffer (4X)

    • DM A Detection Reagent

    • DM C Detection Reagent

    • DM D Detection Reagent

    • Phosphatidylinositol (1mM)

    • Phosphatidylserine (1mM)

    • Stop Reagent C

      View All» Brand Family: Upstate View All» Target Sub-Family: PI3K/PI4K View All» Storage Conditions: 12 months at -70°C View All» Detection Methods: HTRF View All» Packaging: Kit capacity: 1920 wells View All» Gene Symbol:
      • PI3KC2α

      • PI3KC2β

      • PI3KC2γ

        View All» Product Name: PI 3-Kinase Class II HTRF Assay View All» Entrez Gene Number:
        • NM_002645.2

        • NM_002646.3

        • NM_004570.4

          View All» Analytes Available: PI 3-Kinase Class II View All»

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