货号：36-007

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-phospho-PRAK (Thr182) Antibody | 36-007 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Upstate (Millipore) View All» Specificity: phosphorylated PRAK View All» Molecular Weight: ~54kDa View All» Immunogen: peptide corresponding to amino acids surrounding phosphorylated Thr182 of human PRAK. View All» Modifications: Phosphorylation View All» Isotype: IgG View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Quality Assurance: routinely evaluated by immunoblot detected phosphorylated recombinant PRAK. Detection of PRAK is abolished after treatment with lambda phosphatase. View All» Purification Method: Immunoaffinity purified View All» Presentation: 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%. View All» Storage Conditions: 2 years at -20°C View All» UniProt Number: Q8IW41 View All» Entrez Gene Number:
  • NM_003668.2

  • NM_139078.1
    View All» Gene Symbol:
    • MAPKAPK5

    • PRAK
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. View All» UniProt Summary: FUNCTION: SwissProt: Q8IW41 # Mediates stress-induced small heat shock protein 27 phosphorylation.SIZE: 473 amino acids; 54220 Da SUBUNIT: Interacts with SQSTM1.SUBCELLULAR LOCATION: Cytoplasm (Probable). Nucleus. Note=Also observed in the nucleus.TISSUE SPECIFICITY: Expressed ubiquitously.PTM: Phosphorylated on Thr-182; which is the regulatory phosphorylation site and is located on the T-loop/loop 12.SIMILARITY: SwissProt: Q8IW41 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain. View All» Brand Family: Upstate View All» Product Name: Anti-phospho-PRAK (Thr182) Antibody | 36-007 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 200 µg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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