金山科研平台，产品价格货期咨询微信：jinshanbio Assay Type:Solid Phase Sandwich ELISA Format:96-well strip plate Assay Length:4.5 hours Sample Type & Volume Required Per Well:Cell Culture Supernates (50 µL), Serum (10 µL), Platelet-poor EDTA Plasma (50 µL), Platelet-poor Heparin Plasma (50 µL), Saliva (25 µL) Sensitivity:6.29 pg/mL Assay Range:15.6 - 1,000 pg/mL (Serum, Saliva, Cell Culture Supernates, Platelet-poor EDTA Plasma, Platelet-poor Heparin Plasma) Specificity:Natural and recombinant human and mouse PDGF-AA. Recombinant rat PDGF-AA shares 95.8% amino acid sequence identity with recombinant human PDGF-AA. Cross-reactivity: Interference:No significant interference observed with available related molecules. Molecule Information: PDGF-AA Long Name: Platelet-derived Growth Factor AA Entrez Gene IDs: 5154 (Human); 25266 (Rat) Background: PDGF-A, -B, and -D The platelet-derived growth factor (PDGF) family of disulfide-linked dimeric proteins consists of four homodimeric proteins, PDGF-AA, PDGF-BB, PDGF-CC and PDGF-DD, and one heterodimeric protein, PDGF-AB. Members of this protein family act mainly on connective tissue. The dimeric isoforms of PDGF are expressed by different cell types and at different times during embryonic development. All PDGF isoforms are synthesized as inactive precursors and are processed to active forms that contain a PDGF/VEGF cysteine knot domain. Only PDGF-C and PDGF-D, also named spinal cord-derived growth factors SCDGF and SCDGF-B, also contain an N-terminal CUB domain. Mature PDGF dimers bind and induce the homo- or hetero-dimerization of two receptor tyrosine kinases (PDGF R alpha and R beta).