金山科研平台，产品价格货期咨询微信：jinshanbio Assay Type:Solid Phase Sandwich ELISA Format:96-well strip plate Assay Length:3.5 hours Sample Type & Volume Required Per Well:Cell Culture Supernates (50 µL), Serum (10 µL), EDTA Plasma (10 µL), Heparin Plasma (10 µL) Sensitivity:0.035 ng/mL Assay Range:0.156 - 10 ng/mL (Serum, Heparin Plasma, Cell Culture Supernates, EDTA Plasma) Specificity:Natural and recombinant human ANGPTL3 Cross-reactivity: Interference:No significant interference observed with available related molecules. Molecule Information: Angiopoietin-like Protein 3/ANGPTL3 Aliases: AGNPT5; Ang-5; Angiopoietin-5; ANGPTL3 Entrez Gene IDs: 27329 (Human); 30924 (Mouse) Background: Angiopoietin-like 3 Angiopoietin-like 3 (ANGPTL3) is a liver secreted glycoprotein that is structurally related to the angiopoietins, although it does not bind Tie-1 or Tie-2. Full length ANGPTL3 circulates in the plasma as do its proteolytically cleaved coiled coil and fibrinogen-like domains. ANGPTL3 promotes an increase in circulating triglyceride levels by directly inhibiting lipoprotein lipase. ANGPTL3 expression is dysregulated in some strains of obese and diabetic mice.