金山科研平台，产品价格货期咨询微信：jinshanbio Assay Type:Solid Phase Sandwich ELISA Format:96-well strip plate Assay Length:2.5 hours Sample Type & Volume Required Per Well:Cell Culture Supernates (20 µL), Serum (10 µL), EDTA Plasma (10 µL), Heparin Plasma (10 µL), Saliva (10 µL), Urine (10 µL) Sensitivity:0.628 ng/mL Assay Range:1.56 - 100 ng/mL (Serum, Heparin Plasma, Saliva, Cell Culture Supernates, EDTA Plasma, Urine) Specificity:Natural and recombinant human RBP4 Cross-reactivity: Interference:No significant interference observed with available related molecules. Molecule Information: RBP4/Retinol-Binding Protein 4 Entrez Gene IDs: 5950 (Human); 19662 (Mouse); 25703 (Rat) Background: Retinol-binding Protein 4/RBP4 Retinol (also known as vitamin A) is unstable and insoluble in aqueous solution. However, it becomes stable and soluble in plasma due to its tight interaction with RBP4, also known as plasma retinol-binding protein. A prototypic member of the lipocalin superfamily, RBP4 has a beta-barrel structure with a well-defined cavity. It is secreted from the liver in a process requiring the availability of retinol. RBP4 delivers retinol from the liver to the peripheral tissues. In plasma, RBP4-retinol forms a complex with transthyretin (TTR), also known as thyroxine-binding protein and prealbumin. Defects in RBP4 cause retinol-binding protein deficiency, which affects night vision.