金山科研平台，产品价格货期咨询微信：jinshanbio Assay Type:ELISA Development Kit Assay Length:4 hours 40 minutes (after plate preparation) Sample Type & Volume Required:100 µL Sufficient Materials:For fifteen 96-well plates* Range:23.4 - 1,500 pg/mL Specificity:Please see the product datasheet Molecule Information: RBP4/Retinol-Binding Protein 4 Entrez Gene IDs: 5950 (Human); 19662 (Mouse); 25703 (Rat) Background: Retinol-binding Protein 4/RBP4 Retinol (also known as vitamin A) is unstable and insoluble in aqueous solution. However, it becomes stable and soluble in plasma due to its tight interaction with RBP4, also known as plasma retinol-binding protein. A prototypic member of the lipocalin superfamily, RBP4 has a beta-barrel structure with a well-defined cavity. It is secreted from the liver in a process requiring the availability of retinol. RBP4 delivers retinol from the liver to the peripheral tissues. In plasma, RBP4-retinol forms a complex with transthyretin (TTR), also known as thyroxine-binding protein and prealbumin. Defects in RBP4 cause retinol-binding protein deficiency, which affects night vision.