R&D Systems代理DY3667 Mouse Myeloperoxidase DuoSet ELISA, 15 Plate (1 KT)

2025-06-28

货号:DY3667

品牌:R&D Systems

规格:1KT

目录价:¥9280.00

市场价格:¥7424.00

会员价格:¥7424.00

  • 到货时间:3~4周

    金山科研平台,产品价格货期咨询微信:jinshanbio Assay Type:ELISA Development Kit Assay Length:4 hours 40 minutes (after plate preparation) Sample Type & Volume Required:100 µL Sufficient Materials:For fifteen 96-well plates* Range:250 - 16,000 pg/mL Specificity:Please see the product datasheet Molecule Information: Myeloperoxidase/MPO Aliases: Lactoperoxidase; MPO Entrez Gene IDs: 4353 (Human); 17523 (Mouse); 303413 (Rat) Background: Myeloperoxidase (MPO)

    View MPO IHC images.Myeloperoxidase (MPO) is a hemeprotein that belongs to the XPO subfamily of the heme peroxidase superfamily. Myeloperoxidase is synthesized as a preproprotein that undergoes proteolytic processing to generate a disulfide-linked heterodimer of the N-terminal beta-subunit (12 kDa) and C-terminal a subunit (60 kDa). Active myeloperoxidase is a tetramer of two beta-subunits and two alpha-subunits that are also disulfide-linked through the two alpha-subunits. Myeloperoxidase is stored in granules and is an abundant protein in neutrophils and monocytes. Myeloperoxidase is released upon activation to catalyze the formation of powerful oxidants such as hypochlorous acid, which kills microbes. Myeloperoxidase can also lead to tissue damage during chronic inflammation. Unprocessed pro- myeloperoxidase can also be released. By alternative splicing, three isoforms of myeloperoxidase have been described. Human and mouse myeloperoxidase share 87% amino acid sequence identity.

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