R&D Systems代理DY3894 Mouse Thrombomodulin/BDCA-3 DuoSet ELISA, 15 Plate (1 KT)

2025-06-27

货号:DY3894

品牌:R&D Systems

规格:1KT

目录价:¥9280.00

市场价格:¥7424.00

会员价格:¥7424.00

  • 到货时间:3~4周

    金山科研平台,产品价格货期咨询微信:jinshanbio Assay Type:ELISA Development Kit Assay Length:4 hours 40 minutes (after plate preparation) Sample Type & Volume Required:100 µL Sufficient Materials:For fifteen 96-well plates* Range:93.8 - 6,000 pg/mL Specificity:Please see the product datasheet Molecule Information: Thrombomodulin/BDCA-3 Aliases: BDCA-3; CD141; Fetomodulin; THBD; THRM Entrez Gene IDs: 7056 (Human); 21824 (Mouse); 83580 (Rat) Background: Thrombomodulin/CD141

    View Thrombomodulin IHC images.Encoded by the THBD gene, Thrombomodulin is also known as CD141 antigen. Predominantly synthesized by vascular endothelial cells, thrombomodulin inhibits coagulation and fibrinolysis. Thrombomodulin functions as a cell surface receptor and an essential cofactor for active thrombin, which in turn activates protein C and thrombin-activatable fibrinolysis inhibitor (TAFI), also known as carboxypeptidase B2 (CPB2). Mutations in the Thrombomodulin gene can cause inherited thrombophilia. In addition, THBD gene polymorphisims are associated with human disease and thrombomodulin plays a role in thrombosis, stroke, arteriosclerosis, and cancer. For example, increased serum levels of thrombomodulin, due to protease cleavage, have been associated with smoking, cardiac surgery, atherosclerosis, liver cirrhosis, diabetes mellitus, cerebral and myocardial infarction, and multiple sclerosis.

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