货号：AB10033

品牌：Merck Millipore

规格：EA

目录价：￥3468.00

市场价格：￥2947.80

会员价格：￥2774.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-UBXD1 Antibody | AB10033 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes UBXD1. View All» Molecular Weight: ~ 55 kDa View All» Epitope: Entire protein View All» Immunogen: GST-tagged recombinant protein corresponding to the entire protein of human UBXD1. View All» Background Information: UBX domain-containing protein 1 is a component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol. UBX domain-containing protein 1 is also involved in ubiquitin-proteasome systems. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Species Reactivity Note: Demonstrated to react with human, mouse, and rat. Homology to Rhesus monkey is 96%. Homology to Chimpanzee is 99%. View All» Application Notes: Western Blot (SNAP ID) Analysis: 0.5 - 2 µg/ml of this antibody detected UBDX1 on 10 µg of human brain tissue lysate.Immunocytochemistry Analysis: 1:500 dilution from a representative lot was detected in UBXD1 in HeLa, A431, and NIH/3T3 cells. View All» Control: Human brain tissue lysate View All» Quality Assurance: Evaluated by Western Blot in human brain tissue lysate.Western Blot Analysis: 0.5 µg/ml of this antibody detected UBDX1 on 10 µg of human brain tissue lysate. View All» Purification Method: Affinity Purfied View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q9BZV1 View All» Entrez Gene Number: NP_079517 View All» Gene Symbol:
  • UBXN6

  • UBXD1

  • UBXDC2
    View All» Alternate Names:
    • UBX domain containing 1

    • UBX domain protein 6

    • UBX domain-containing 1

    • UBX domain-containing 2

    • UBX domain-containing protein 1
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunocytochemistry
        View All» UniProt Summary: FUNCTION: Acts in a complex with VCP and cooperates with USP7 in promoting MDM2 deubiquitination and stabilization. MDM2 stabilization leads to MDM2-dependent TP53 degradation. SUBUNIT STRUCTURE: Interacts with VCP through the PUB domain. Interacts with SYVN1, HERPUD1, MDM2 and USP7. SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Cytoplasm › cytoskeleton › centrosome. Note: Localizes at the centrosome both in interphase and during mitosis. TISSUE SPECIFICITY: Enhanced expression in testis.SEQUENCE SIMILARITIES: Contains 1 PUB (PUG) domain.Contains 1 UBX domain. View All» Product Name: Anti-UBXD1 View All» Concentration: 1.0 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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