货号：AB10041

品牌：Merck Millipore

规格：

目录价：￥3639.00

市场价格：￥3093.15

会员价格：￥2911.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-UBX domain-containing protein 1 (UBXN1/SAKS1) Antibody | AB10041 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes full-length UBX domain-containing protein 1. View All» Molecular Weight: ~39 kDa View All» Epitope: Full Length Protein View All» Immunogen: GST-tagged recombinant protein corresponding to full-length human UBX domain-containing protein 1. View All» Background Information: UBX domain-containing protein 1 (UBXN1 or SAKS1) is a component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol. UBX domain-containing protein 1 is also involved in ubiquitin-proteasome systems. View All» Species Reactivity:

• Human

• Rat

• Mouse
  View All» Species Reactivity Note: Demonstrated to react with human. mouse and rat. View All» Application Notes: Immunoprecipitation Analysis: 20 µg from a previous lot of this antibody was used in immunoprecipitation in 1 mL of mouse brain tissue lysate.Western Blot (SNAP ID) Analysis: 2 µg/mL from a previous lot detected UBX domain-containing protein 1 in 10 µg of human fetal tissue lysate. View All» Control: Human fetal brain tissue lysate View All» Quality Assurance: Evaluated by Western Blot in human fetal brain lysate.Western Blot Analysis: 0.1 µg/mL of this antibody detected UBX domain-containing protein 1 in 10 µg of human fetal brain lysate. View All» Purification Method: Affinity Purfied View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. View All» Storage Conditions: Stable at 2-8°C for 1 year from date of recepit. View All» UniProt Number: Q04323 View All» Entrez Gene Number: NP_056937.2 View All» Gene Symbol:
  • 2B28

  • LOC51035

  • SAKS1

  • UBXD10
    View All» Alternate Names:
    • SAPK substrate protein 1

    • UBA/UBX 33.3 kDa protein

    • UBX domain protein 1
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunoprecipitation
        View All» UniProt Summary: FUNCTION: Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulun that are retrotranslocated in the cytosol. Involved in ubiquitin-proteasome systems By similarity.SUBUNIT STRUCTURE: Component of a complex required to couple retrotranslocation, ubiquitination and deglycosylation composed of NGLY1, SAKS1, AMFR, VCP and RAD23B. Interacts with HOMER2 By similarity. Interacts directly with VCP. Binds polyubiquitin.SUBCELLULAR LOCATION: Cytoplasm By similarity. SEQUENCE SIMILARITIES: Contains 1 UBA domain.Contains 1 UBX domain. View All» Product Name: Anti-UBX domain-containing protein 1 (UBXN1/SAKS1) View All» Concentration: 0.5 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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