货号：AB10076

品牌：Merck Millipore

规格：EA

目录价：询价

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-3A5 Antibody | AB10076 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Molecular Weight: 57kDa View All» Epitope: AA 42 to 83 View All» Immunogen: Recombinant human 3A5 View All» Background Information: CYP3A (cytochrome P450, family 3, subfamily A), is a member of the cytochrome P450 superfamily of monooxygenase enzymes which catalyze many reactions involved in drug metabolism and the synthesis of cholesterol, steroids and other lipids. View All» Species Reactivity: Human View All» Application Notes: Western Blot: 1:5000 View All» Quality Assurance: Routinely evaluated by immunoblot. View All» Presentation: Raw rabbit serum with 0.05% sodium azide. View All» Storage Conditions: Maintain at -20°C for up to 12 months from date of receipt. View All» UniProt Number: P20815 View All» Entrez Gene Number: NP_000768 View All» Gene Symbol:

• CYPIIIA5

• P450-PCN3

• EC 1.14.14.1

• HLp2
  View All» Alternate Names: Cytochrome P450 3A5 View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: This gene,CYP3A5, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. This cluster includes a pseudogene, CYP3A5P1, which is very similar to CYP3A5. This similarity has caused some difficulty in determining whether cloned sequences represent the gene or the pseudogene. View All» UniProt Summary: FUNCTION: SwissProt: P20815 # Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. SIZE: 502 amino acids; 57109 Da SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. SIMILARITY: SwissProt:P20815 # Belongs to the cytochrome P450 family. View All» Brand Family: Chemicon View All» Product Name: Anti-3A5 Antibody | AB10076 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 50 µL View All» Format: Serum View All» Host: Rabbit View All»
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