货号:AB10093
品牌:Merck Millipore
规格:
目录价:¥3789.00
市场价格:¥3220.65
会员价格:¥3031.20
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Description:
Anti-GST θ 1 Antibody | AB10093
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Promotional Text:
Special Shipping Offer on Antibodies100% Performance Guaranteed
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Trade Name:
Chemicon (Millipore)
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Molecular Weight:
26kDa
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Immunogen:
Recombinant GST Theta 1
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Species Reactivity:
Human
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Quality Assurance:
Routinely evaluated by immunoblot.
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Purification Method:
Serum
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Presentation:
Raw Rabbit Serum with 0.1% Sodium Azide
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Storage Conditions:
1 year at 2-8°C from date of shipment
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UniProt Number:
P30711
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Entrez Gene Number:
NM_000853.1
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Gene Symbol:
GSTT1
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
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Entrez Gene Summary:
Glutathione S-transferase (GST) theta 1 (GSTT1) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1 and GSTT2. The GSTT1 and GSTT2 share 55% amino acid sequence identity and both of them were claimed to have an important role in human carcinogenesis. The GSTT1 gene is located approximately 50kb away from the GSTT2 gene. The GSTT1 and GSTT2 genes have a similar structure, being composed of five exons with identical exon/intron boundaries.
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UniProt Summary:
FUNCTION: SwissProt: P30711 # Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Acts on 1,2- epoxy-3-(4-nitrophenoxy)propane, phenethylisothiocyanate 4- nitrobenzyl chloride and 4-nitrophenethyl bromide. Displays glutathione peroxidase activity with cumene hydroperoxide.SIZE: 240 amino acids; 27335 Da SUBUNIT: Homodimer.SUBCELLULAR LOCATION: Cytoplasm.TISSUE SPECIFICITY: Found in erythrocyte. Expressed at low levels in liver. In lung, expressed at low levels in Clara cells and ciliated cells at the alveolar/bronchiolar junction. Absent from epithelial cells of larger bronchioles.SIMILARITY: SwissProt: P30711 ## Belongs to the GST superfamily. Theta family.
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Brand Family:
Chemicon
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Product Name:
Anti-GST θ 1 Antibody | AB10093
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Antibody Type:
Polyclonal Antibody
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Qty/Pk:
50 µL
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Format:
Serum
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Host:
Rabbit
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