货号：AB10512

品牌：Merck Millipore

规格：

目录价：￥4383.00

市场价格：￥3725.55

会员价格：￥3506.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Caspase 6 (active form) Antibody | AB10512 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: The antibody recognizes the large subunit of active Caspase 6. View All» Molecular Weight: ~ 18 kDa Observed. UniProtKB/TrEMBL Q6AZ23 lists a MW of 31,574 Da for the full length protein which is normally cleaved into a large and small subunit. View All» Epitope: C-terminus of the large subunit of Caspase 6 View All» Immunogen: KLH-conjugated linear peptide corresponding to the C-terminus of the large subunit of rat Caspase 6. View All» Background Information: Caspases are a family of cytosolic aspartate-specific cysteine proteases involved in the initiation and execution of apoptosis. Caspase 6 is a major apoptotic executioner (1,2). It exists as a pro-domain protein and is cleaved by caspase-3 into two subunits, an 18 kDa and a 10 kDa subunit that dimerize to form the active enzyme (3). Caspase 6 cleaves among many different intracellular proteins, nuclear lamins. Lamins play a significant role in maintaining the integrity of the cell membrane, and their cleavage results in subsequent cellular breakdown and death (4). View All» Species Reactivity:

• Rat

• Human

• Bovine

• Feline

• Chimpanzee
  View All» Species Reactivity Note: Demonstrated to react with human and rat. Predicted to react with bovine, feline, and chimpanzee based on 100% sequence homology. View All» Application Notes: Immunohistochemistry Analysis: 1:600 dilution from a previous lot detected Caspase 6 in colorectal carcinoma tissue. View All» Control: Rat kidney tissue lysate View All» Quality Assurance: Evaluated by Western Blot in rat kidney tissue lysate.Western Blot Analysis: 0.5 µg/mL of this antibody detected Caspase 6 in 10 µg of rat kidney tissue lysate. View All» Purification Method: Affinity Purfied View All» Presentation: Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at 2-8°C from date of receipt. View All» UniProt Number: Q6AZ23 View All» Entrez Gene Number: NP_113963 View All» Gene Symbol:
  • CASP-6

  • MCH2
    View All» Alternate Names:
    • Apoptotic protease Mch-2

    • caspase 6

    • caspase 6, apoptosis-related cysteine peptidase

    • caspase 6, apoptosis-related cysteine protease
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
      • Western Blotting

      • Immunohistochemistry
        View All» Entrez Gene Summary: Member of the cysteine-aspartic acid protease (caspase) family that plays a terminal role in apoptosis [RGD]. View All» UniProt Summary: SEQUENCE SIMILARITIES: Belongs to the peptidase C14A family. View All» Product Name: Anti-Caspase 6 (active form) View All» Concentration: 1.0 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μg View All» Format: Affinity Purified View All» Host: Rabbit View All»
        © 金山科研平台是专业的授权总代理区域代理经销平台。
        © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
        © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
        © 本文地址：https://www.16ao.com/thread-151482.htm
        © Merck Millipore代理AB10512 Anti-Caspase-6, large subunit p20，产品报价联系微信jinshanbio