货号：AB10517

品牌：Merck Millipore

规格：EA

目录价：￥3468.00

市场价格：￥2947.80

会员价格：￥2774.40

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-BAT3 (Protein G3) Antibody | AB10517 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes BAT3 at and around the N-terminus. View All» Molecular Weight: Predicted MW: ~120 kDaObserved MW: ~140 kDaAnalysis of endogenously expressed BAT3 in various tissues including the kidney reveals the existence of a 140 kDa full-length protein as well as truncated forms of BAT3 whose expression is developmentally regulated (Kwak, J., et al., 2008). View All» Epitope: N-terminus View All» Immunogen: His-tagged recombinant protein corresponding to the N-terminal region of BAT3. View All» Background Information: BAT3, also known as protein G3 or HLA-B associated transcript 3, is a nuclear protein. Little is known about the function of BAT3; however, it has been shown to regulate apoptosis. In addition, BAT3 deficient mice had developmental defects in their lungs, kidneys, and brains. Human BAT3, orthologous to rat BAT3, is primarily expressed in the testis. View All» Species Reactivity:

• Human

• Mouse

• Rat
  View All» Species Reactivity Note: Proven to react with human, mouse, and rat. View All» Application Notes: Western Blot Analysis: A 1:1,000 dilution from a previous lot detected BAT3 in various lysates using western blot. View All» Control: Rat thymus lysate View All» Quality Assurance: Evaluated by Western Blot in Rat thymus lysate.Western Blot Analysis: A 1:1,000 dilution of this antibody detected BAT3 in 10 µg of Rat thymus lysate. View All» Purification Method: Unpurified View All» Presentation: Rabbit polyclonal serum in 0.5% sodium azide. View All» Storage Conditions: Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. View All» UniProt Number: P46379 View All» Entrez Gene Number: NP_476512 View All» Gene Symbol:
  • BAG-6

  • BAG6

  • D6S52E

  • G3

  • OTTHUMP00000029239

  • scythe
    View All» Alternate Names:
    • HLA-B associated transcript 3

    • HLA-B associated transcript-3

    • HLA-B-associated transcript 3

    • Protein G3

    • large proline-rich protein BAT3
      View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» UniProt Summary: FUNCTION: Plays a role in ricin-induced apoptosis. SUBUNIT STRUCTURE: Interacts with ricin A chain. SUBCELLULAR LOCATION: Nucleus. Note: The C-terminal fragment generated by caspase-3 is cytoplasmic. PTM: Cleavage by CASP3 releases a C-terminal peptide that plays a role in ricin-induced apoptosis.SEQUENCE SIMILARITIES: Contains 1 ubiquitin-like domain.SEQUENCE CAUTION: The sequence CAI18318.2 differs from that shown. Reason: Erroneous gene model prediction. View All» Product Name: Anti-BAT3 (Protein G3) View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Unpurified View All» Host: Rabbit View All»
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