货号：AB10522

品牌：Merck Millipore

规格：100UL

目录价：￥4967.00

市场价格：￥4221.95

会员价格：￥3973.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Neuropilin-2 Antibody | AB10522 View All» Replaces: AB9160 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes Neuropilin-2. View All» Molecular Weight: 130 kDa View All» Epitope: Unknown View All» Immunogen: His-tagged partial recombinant rat Neuropilin-2 protein. View All» Isotype: IgG View All» Background Information: There are two forms of Neuropilin: Neuropilin-1 and Neuropilin-2. These are non–tyrosine kinase receptors that bind to VEGF and semaphorins (SEMA3A, SEMA3B, and SEMA3F) and play an important role in the critical functioning of the nervous system. Neuropilin-2 is expressed in tumor cells, and mature and developing endothelial cells and vascular smooth muscle cells. This expression has been associated with tumor angiogenesis and progression. View All» Species Reactivity: Mouse View All» Species Reactivity Note: Proven to react with mouse. View All» Control: Mouse P1 brain tissue lysate View All» Quality Assurance: Evaluated by Western Blot in mouse P1 brain tissue lysate.Western Blot Analysis: 1:1000 dilution of this antibody detected Neuropilin-2 on 10 µg of mouse P1 brain tissue lysate. View All» Purification Method: Unpurified View All» Presentation: Unpurified Rabbit Serum containing 0.05% Sodium Azide. View All» Storage Conditions: Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. View All» UniProt Number: O35276 View All» Entrez Gene Number: NP_110496.1 View All» Gene Symbol:

• NRP2

• NP2

• NPN2

• PRO2714

• VEGF165R2

• VEGF1265R2, 1110048P06Rik
  View All» Alternate Names:
  • Vascular endothelial cell growth factor 165 receptor 2

  • neuropilin 2

  • receptor for VEGF165 and semaphorins class 3

  • vascular endothelial growth factor-165 receptor 2
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunohistochemistry

    • Immunoprecipitation

    • Immunofluorescence
      View All» UniProt Summary: FUNCTION: High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF.SUBUNIT STRUCTURE: Heterodimer with NRP1 Probable. Binds PLXNB1 By similarity.SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. TISSUE SPECIFICITY: Found in certain neuronal populations of the CNS and in other non-neuronal tissues including mesenchymal tissue lining in the ribs.DEVELOPMENTAL STAGE: The expression pattern is very dynamic and is developmentally regulated.SEQUENCE SIMILARITIES: Belongs to the neuropilin family.Contains 2 CUB domains.Contains 2 F5/8 type C domains.Contains 1 MAM domain. View All» Product Name: Anti-Neuropilin-2 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Target / Localization: Plasma membrane View All» Format: Serum View All» Host: Rabbit View All»
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