货号：AB10535

品牌：Merck Millipore

规格：100UL

目录价：￥5666.00

市场价格：￥4816.10

会员价格：￥4532.80

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Neurogenin-3 (rabbit) Antibody | AB10535 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: This antibody recognizes Neurogenin-3 at the N-terminus. View All» Molecular Weight: 32 kDa View All» Epitope: N-terminus View All» Immunogen: GST-tagged recombinant protein corresponding to the N-terminus of mouse Neurogenin-3. View All» Isotype: IgG View All» Background Information: Neurogenins are a family of bHLH transcription factors involved in specifying neuronal differentiation. They are related to Drosophila atonal. The neurogenins (ngns) make up one of these atonal-related gene families. In neural crest cells, the atonal-related neurogenin family is particularly important for the sensory lineage (Neurogenins Are Essential for the Formation of dorsal root ganglia), while the achaete-scute homologue ash1 (Mash1) is important for aspects of autonomic neurogenesis (mash1 is essential for noradrenergic differentiation). Neurogenin-3 also promotes pancreatic development. View All» Species Reactivity: Mouse View All» Species Reactivity Note: Demonstrated to react with mouse. View All» Application Notes: Immunohistochemistry Analysis: A 1:500 dilution from a previous lot detected Neurogenin-3 in mouse embryo E12.5+ tissue. View All» Control: mNgn3 transfected and wildtype rabbit reticulocyte lysates View All» Quality Assurance: Evaluated by Western Blot in mNgn3 transfected and wildtype rabbit reticulocyte lysates.Western Blot Analysis: A 1:1,000 dilution of this antibody detected Neurogenin-3 on 10 µg of mNgn3 transfected rabbit reticulocyte lysates. View All» Purification Method: Unpurified View All» Presentation: Unpurified rabbit polyclonal serum containing 0.05% sodium azide. View All» Storage Conditions: Stable for 1 year at -20°C from date of receipt.Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. View All» UniProt Number: P70661 View All» Entrez Gene Number: NP_033849 View All» Gene Symbol:

• NEUROG3

• ATOH5

• Atoh5

• ngn3

• NGN3

• MATH4B

• Math4B
  View All» Alternate Names:
  • Neurogenin 3

  • NGN3

  • Neurogenin3
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunohistochemistry
      View All» UniProt Summary: FUNCTION: Involved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types. SUBUNIT STRUCTURE: Efficient DNA binding requires dimerization with another bHLH protein.SUBCELLULAR LOCATION: Nucleus Potential. SEQUENCE SIMILARITIES: Contains 1 basic helix-loop-helix (bHLH) domain. View All» Product Name: Anti-Neurogenin-3 (rabbit polyclonal) View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Serum View All» Host: Rabbit View All»
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      © Merck Millipore代理AB10535 Anti-Neurogenin-3 (rabbit) Antibody;抗-神经原素-3（兔）抗体store at -20℃，产品报价联系微信jinshanbio