货号：AB1247

品牌：Merck Millipore

规格：

目录价：￥4264.00

市场价格：￥3624.40

会员价格：￥3411.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Cytochrome P450 Enzyme CYP1A1 Antibody | AB1247 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Reacts with rat cytochrome P450 enzyme CYP1A1 in hepatic microsomal fraction. No cross-reactivity with other cytochrome P450 enzymes including CYP1A2. View All» Molecular Weight: 59 kDa View All» Immunogen: Synthetic peptide View All» Species Reactivity: Rat View All» Application Notes: Western blot Immunohistochemistry on frozen and formaldehyde treated sections. Optimal working dilutions must be determined by end user. View All» Control: Liver tissue View All» Purification Method: Unpurified View All» Presentation: Rabbit antiSerum. Liquid containing no preservative View All» Storage Conditions: Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. View All» UniProt Number: P04798 View All» Entrez Gene Number: NM_000499.2 View All» Gene Symbol:

• CYP1A1

• CP11

• P1-450

• CYPIA1

• P450-C

• CYP1

• P450DX

• P450-P1

• AHRR

• AHH
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
  • Immunohistochemistry

  • Western Blotting
    View All» Entrez Gene Summary: This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. View All» UniProt Summary: FUNCTION: SwissProt: P04798 # Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.SIZE: 512 amino acids; 58165 Da SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.TISSUE SPECIFICITY: Lung, lymphocytes and placenta.SIMILARITY: SwissProt: P04798 ## Belongs to the cytochrome P450 family. View All» Brand Family: Chemicon View All» Product Name: Anti-Cytochrome P450 Enzyme CYP1A1 Antibody | AB1247 View All» Concentration: Variable View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 μL View All» Format: Serum View All» Host: Rabbit View All»
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