Merck Millipore代理AB1269 CYTOCHR P450 CYP2C8-9-19, RBX-100UL;已停产

2025-06-28

货号:AB1269

品牌:Merck Millipore

规格:EA

目录价:询价

金山科研平台,产品价格货期咨询微信:jinshanbio Description: Anti-Cytochrome P450 Enzyme CYP2C8/9/19 Antibody, CYP2C12 | AB1269 View All» Replaces: MAB3524 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Reacts with cytochrome P450 CYP2C8, CYP2C9 and CYP2C19 in human hepatic microsomal fraction and to CYP2C12 in rat hepatic microsomal fraction. View All» Immunogen: Synthetic peptide View All» Species Reactivity:

  • Human

  • Rat

    View All» Application Notes: Western blot: human CYP2C8/9/19 and rat CYP2C12 migrate at approximately 56 kDa on SDS-PAGE. Immunohistochemistry Optimal working dilutions must be determined by end user. View All» Presentation: Rabbit antiserum. Liquid. Contains no preservatives. View All» Storage Conditions: Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles. View All» UniProt Number:
    • P10632

    • P11712

    • P33261

      View All» Entrez Gene Number: NM_000770.3 View All» Gene Symbol:
      • CYP2C8

      • CYPIIC8

      • CPC8

        View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
        • Immunohistochemistry

        • Western Blotting

          View All» Entrez Gene Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. View All» UniProt Summary: FUNCTION: SwissProt: P33261 # Responsible for the metabolism of a number of therapeutic agents such as the anticonvulsant drug S-mephenytoin, omeprazole, proguanil, certain barbiturates, diazepam, propranolol, citalopram and imipramine.SIZE: 490 amino acids; 55931 Da SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.SIMILARITY: SwissProt: P33261 ## Belongs to the cytochrome P450 family. View All» Brand Family: Chemicon View All» Product Name: Anti-Cytochrome P450 Enzyme CYP2C8/9/19 Antibody, CYP2C12 | AB1269 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Format: Serum View All» Host: Rabbit View All»

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