货号：AB15102

品牌：Merck Millipore

规格：

目录价：￥4110.00

市场价格：￥3493.50

会员价格：￥3288.00

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Mint-1 Antibody | AB15102 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Mint-1. By Western blot the antibody recognizes a band at ~130 kDa in rat brain lysate. View All» Immunogen: Synthetic peptide from rat. View All» Species Reactivity: Rat View All» Application Notes: Western blot: 1:5,000-1:10,000 using ECL (5 min exposure)Optimal working dilutions must be determined by the end user. View All» Purification Method: Serum View All» Presentation: Liquid View All» Storage Conditions: Maintain at -20degC in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles. View All» UniProt Number: Q02410 View All» Entrez Gene Number: NM_001163.2 View All» Gene Symbol:

• APBA1

• D9S411E

• X11

• X11A

• X11ALPHA

• MINT1
  View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications: Western Blotting View All» Entrez Gene Summary: The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adaptor protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilises APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. View All» UniProt Summary: FUNCTION: SwissProt: Q02410 # Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta- amyloid precursor protein (APP) and hence formation of beta-APP.SIZE: 837 amino acids; 92865 Da SUBUNIT: Part of a multimeric complex containing Munc18-1 and syntaxin-1. Also part of the brain-specific heterotrimeric complex LIN-10/X11-alpha, LIN-2/CASK, and LIN7. Binds to the cytoplasmic domain of amyloid protein (APP).TISSUE SPECIFICITY: Brain and spinal cord.DOMAIN: SwissProt: Q02410 Composed of an N-terminal domain that binds Munc18-1 and LIN-2/CASK, a middle phosphotyrosine-binding domain (PID/PTB) that mediates binding with the cytoplasmic domain of the beta-amyloid precursor protein, and two C-terminal PDZ domains thought to attach proteins to the plasma membrane.SIMILARITY: Contains 2 PDZ (DHR) domains. & Contains 1 PID domain. View All» Brand Family: Chemicon View All» Product Name: Anti-Mint-1 Antibody | AB15102 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Target / Localization: Presynaptic View All» Format: Serum View All» Host: Rabbit View All»
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