货号：AB15138

品牌：Merck Millipore

规格：100Ug

目录价：￥4967.00

市场价格：￥4221.95

会员价格：￥3973.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Nogo Receptor Antibody | AB15138 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Specificity: Cat. # AB15138 recognizes the mature form of Nogo Receptor. View All» Molecular Weight: ~50.9 kDa View All» Epitope: Mature Form View All» Immunogen: Recombinant protein. View All» Background Information: Axons are essential for neuronal communication but they do not regenerate after injury to the adult mammalian brain or spinal cord. Failed regeneration is due in part to the production of a potent axonal growth inhibitor, Nogo, by myelinating cells. The finding of a high affinity axonal receptor for the extracellular domain of Nogo provides the first insight into the basis of Nogo action. Disrupting the interaction of Nogo with the Nogo-66 receptor may facilitate axonal regeneration in vivo. The protein is dubbed the Nogo receptor because it binds with several other proteins that block neural growth. It is found to be ubiquitous in the brain and spinal cord. View All» Species Reactivity:

• Mouse

• Rat

• Human
  View All» Species Reactivity Note: Mouse and rat. May react with human and primate based on sequence homology. Reactivity with other species has not been determined. View All» Application Notes: Non-Lot Specific Tested Application 1:Immunohistochemistry: Working dilutions of 1:50-1:500 in rat brain and spinal cord (paraffin embedded) View All» Control: Mouse cerebellum lysate View All» Quality Assurance: Routinely tested on mouse cerebellum lysate.Lot Specific Tested Application 1: Western Blot View All» Purification Method: Protein A purfied View All» Presentation: Purified in PBS with 0.1% NaN3 View All» Storage Conditions: Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt. View All» UniProt Number: Q99PI8 View All» Entrez Gene Number: NM_022982 View All» Alternate Names:
  • Reticulon-4 receptor

  • Nogo receptor

  • NgR

  • Nogo-66 receptor

  • Nogor

  • Rtn4r
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunohistochemistry
      View All» Product Name: Anti-Nogo Receptor View All» Concentration: 1 mg/mL View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µg View All» Format: Purified View All» Host: Rabbit View All»
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