货号：AB1526P

品牌：Merck Millipore

规格：20Ug

目录价：￥6127.00

市场价格：￥5207.95

会员价格：￥4901.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Nerve Growth Factor-β Antibody, pain | AB1526P View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Nerve growth factor-beta (NGF). Less than 1% cross-reactivity against recombinant human BDNF, NT3 and NT4 by ELISA. View All» Immunogen: Mouse nerve growth factor-beta purified from salivary glands. View All» Species Reactivity:

• Chicken

• Human

• Mouse

• Rat
  View All» Non-Reactive Species: Bovine View All» Application Notes: Immunohistochemistry: 1-2 μg/mL (see suggested protocol). Immunoblotting: 1-2 μg/mL Bioassays (Inhibition of biological activity in vitro): 1-2 μg/mL in vivo animal studies: use neat ELISA: 1-2 μg/mL Optimal working dilutions must be determined by the end user. BIOLOGICAL ACTIVITY: This antibody completely inhibits neuron survival and the outgrowth actions of mouse NGF in chicken dorsal root ganglion in vitro. View All» Presentation: Affinity purified immunoglobulin. Lyophilized from PBS. Contains no preservative. Reconstitute to desired volume with sterile distilled water. Suggested concentration 0.5-1.0 mg/mL. View All» Storage Conditions: Maintain at lyophilized material at -20 to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20 to -70°C in undiluted aliquots for up to six months. Avoid repeated freeze/thaw cycles. View All» UniProt Number: P01138 View All» Entrez Gene Number: NM_002506.2 View All» Gene Symbol:
  • NGFB

  • MGC161426

  • HSAN5

  • NGF

  • Beta-NGF

  • MGC161428
    View All» Alternate Names: NGFbeta View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • ELISA

    • Western Blotting

    • Immunohistochemistry

    • Affects Function
      View All» Entrez Gene Summary: This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. View All» UniProt Summary: FUNCTION: SwissProt: P01138 # Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons.SIZE: 241 amino acids; 26959 Da SUBUNIT: Homodimer.SUBCELLULAR LOCATION: Secreted.DISEASE: SwissProt: P01138 # Defects in NGFB are the cause of hereditary sensory and autonomic neuropathy type 5 (HSAN5) [MIM:608654]. Hereditary sensory and autonomic neuropathies are characterized by loss of pain sensation in combination with other sensory and/or autonomic abnormalities. HSAN5 patients manifest loss of pain perception and impaired temperature sensitivity, ulcers, and in some cases self- mutilation. The autonomic involvement is variable.SIMILARITY: SwissProt: P01138 ## Belongs to the NGF-beta family. View All» Brand Family: Chemicon View All» Product Name: Anti-Nerve Growth Factor-β Antibody, pain | AB1526P View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 20 µg View All» Format: Affinity Purified View All» Host: Rabbit View All»
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