货号：AB1530

品牌：Merck Millipore

规格：100UL

目录价：￥5974.00

市场价格：￥5077.90

会员价格：￥4779.20

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-Peripherin Antibody | AB1530 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: Recognizes Peripherin. The antibody stains a ~57 kDa band cleanly and specifically and does not stain vimentin, GFAP, alpha-internexin or any of the neurofilament subunits. Strong staining on rat, mouse, human, pig and cow peripherin. Does not stain chicken, quail or other more distantly related species which appear to lack peripherin. View All» Molecular Weight: 56-58 kDa View All» Immunogen: Electrophoretically pure trp-E-peripherin fusion protein [Dev. Brain Res. (1990) 57:235-248], containing all but the 4 N terminal amino acids of rat peripherin. Fusion protein purified from bacterial inclusion bodies by DEAE-cellulose chromatography in 6 M urea followed by preparative SDS-PAGE. View All» Background Information: Peripherin is a 56-58 kDa type III intermediate filament protein (Portier et al. 1983), expressed in motor, sensory and sympathetic system neurons as well as neuroendocrine skin carcinomas and certain melanocytic tumors. It is often used an indicator of enteric ganglion cell density in normal and diseased (e.g. Hirschsprung's disease) states. Abnormal inclusions containing peripherin have also been reported in ALS. During normal, late neurogenesis peripherin appears after the expression of nestin, vimentin, alpha-internexin and neurofilaments and is involved in the differentiation of neurons, namely of the peripheral nervous system, and also probably in axonal regeneration. Peripherin is not related to peripherin-RDS, a photoreceptor protein associated with retinal degeneration and blindness. View All» Species Reactivity:

• Human

• Rat

• Mouse

• Bovine

• Pig
  View All» Species Reactivity Note: Strong staining on rat and human. Cross-reacts with mouse, pig, and bovine. Other species not tested. View All» Application Notes: Additional Research ApplicationsImmunohistochemistry: A previous lot of this antibody was used at 1:100-1:200 dilution. It is suggested that the antibody be used on frozen sections fixed in acetone at -20°C. AB1530 will work on tissue fixed for one hour or less in fresh 4% paraformaldehyde. It has been reported that this antibody can be used on paraffin embedded tissue sections. See Cell & Tissue Research (1997) 288:11-23 & European J. Dermatology (1998) 8:339-342.Electron Microscopy: A previous lot of this antibody was used on Electron Microscopy.Optimal working dilutions and protocols must be determined by end user. View All» Control: Rat sensory neurons, rat spinal cord homogenate and peripheral nerve homogenate. View All» Quality Assurance: Routinely evaluated by Western Blot on PC12 lysates.Western Blot Analysis: 1:1000 dilution of this lot detected peripherin on 10 μg of PC12 lysates. View All» Purification Method: Unpurified View All» Presentation: Rabbit polyclonal antisera, no preservatives. View All» Storage Conditions: Stable for 1 year at -20°C in undiluted aliquots from date of receipt. Handling Recommendations: Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. View All» UniProt Number: P41219 View All» Entrez Gene Number: NP_006253 View All» Gene Symbol:
  • PRPH

  • Peripherin

  • PRPH1

  • peripherin

  • NEF4
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Immunohistochemistry

    • Immunohistochemistry (Paraffin)

    • Western Blotting
      View All» Entrez Gene Summary: This gene encodes a cytoskeletal protein found in neurons of the peripheral nervous system. The encoded protein is a type III intermediate filament protein with homology to other cytoskeletal proteins such as desmin, and is a different protein that the peripherin found in photoreceptors. Mutations in this gene have been associated with susceptibility to amyotrophic lateral sclerosis. View All» UniProt Summary: FUNCTION: SwissProt: P41219 # Class-III neuronal intermediate filament protein.SIZE: 470 amino acids; 53651 Da SIMILARITY: SwissProt: P41219 ## Belongs to the intermediate filament family. View All» Brand Family: Chemicon View All» Product Name: Anti-Peripherin Antibody | AB1530 View All» Concentration: Variable View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µL View All» Target / Localization: Cytoplasmic, soma, early neurites, Peripheral neurons View All» Format: Serum View All» Host: Rabbit View All»
      © 金山科研平台是专业的授权总代理区域代理经销平台。
      © 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
      © 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
      © 本文地址：https://www.16ao.com/thread-152107.htm
      © Merck Millipore代理AB1530 Anti-Peripherin Antibody;抗外周蛋白抗体store at -20℃，产品报价联系微信jinshanbio