货号：AB15301

品牌：Merck Millipore

规格：

目录价：￥3732.00

市场价格：￥3172.20

会员价格：￥2985.60

金山科研平台，产品价格货期咨询微信：jinshanbio Description: Anti-RanBPM Antibody | AB15301 View All» Promotional Text: Special Shipping Offer on Antibodies100% Performance Guaranteed View All» Trade Name: Chemicon (Millipore) View All» Specificity: RanBPM View All» Molecular Weight: 71 kDa View All» Immunogen: Synthetic Peptide View All» Background Information: RanBPM is shown to physically interact with Plexin-A1, and the RanBPM/Plexin complex is regulated by MICAL expression. Overexpression of RanBPM cooperates with PlexinA1 to reduce non-neuronal cell spreading and strongly inhibit axonal outgrowth in vitro and in vivo. A truncated RanBPM protein blocks Sema3A responsiveness in non-neuronal and neuronal cells. Suppression of RanBPM expression reduces Sema3A responsiveness. Thus, RanBPM is a mediator of Sema3A signaling through Plexin-A. RanBPM has the potential to link Plexin-A receptors to retrograde transport and microtubule function in axonal guidance View All» Species Reactivity:

• Mouse

• Human

• Rat
  View All» Application Notes: Western blot Analysis: RanBPM can be detected at 1/1000 in rat, mouse and human brainImmunohistochemistry: 1:50 and 1:500 dilution of Cat. # AB15301 was tested on human normal, tumor tissue and tonsil tissue. Optimal working dilutions must be determined by the end user. View All» Control: Tested on mouse, rat and human brain View All» Purification Method: Immunoaffinity purified View All» Presentation: Purified Antibody in PBS with 0.1% NaN3 View All» Storage Conditions: Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt. View All» UniProt Number: Q99549 View All» Gene Symbol:
  • MPP8

  • MPHOSPH8

  • TWA3
    View All» Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. View All» Key Applications:
    • Western Blotting

    • Immunohistochemistry
      View All» Product Name: Anti-RanBPM Antibody | AB15301 View All» Antibody Type: Polyclonal Antibody View All» Qty/Pk: 100 µg View All» Target / Localization: Cytoplasmic, growth cone View All» Format: Affinity Purified View All» Host: Rabbit View All»
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